A successful physician and devoted family man, John Dolittle (Murphy) seems to have the world by the tail, until a long-suppresses talent possessed as a child - the ability to communicate with animals- is suddenly reawakened with a vengeance! Now every creature within squawking distance wants the good doctor's advice, unleashing an outrageous chain of events that turn his world upside down!

Featuring an all-star menagerie of voice talent (including Chris Rock, John Leguizamo, Norm MacDonald, Albert Brooks, Gary Shandling and Ellen DeGeneres), this wild and woolly free-for-all is your prescription for hilarious hijinks and "mischievous fun!" (The New York Times)