Pure Pharmaceutical 
Niacinamide (B3) and N-Acetyl Glucosamine (NAG) Powder

Nature & Nurture, NY USA
   
Niacinamide (VB3) : Vitamin B at its Best

Proven to: Increase  production of ceramides and fatty acids -- two  key components of your skin's outer protective  barrier. "As that barrier is strengthened, skin  is better able to keep moisture in and irritants  out—making B3 a great ingredient if your  complexion is dry or sensitive," says Leslie S.  Baumann, MD, director of the University of Miami  Cosmetic Medicine and Research Institute. In one  study, a moisturizer with niacinamide improved  the flushing and blushing of rosacea, a common  condition that can worsen with age. Another B3  skin care benefit: It inhibits the transfer of  pigment to skin cells, minimizing dark spots.

What is Niacinamide:
Niacinamide,  is the active component of vitamin B3.When  vitamin B3, or niacin, combines with amino acids  of another molecule, the chemical reaction  produces niacinamide, Niacinamide is a potent cell-communicating ingredient that offers multiple benefits for aging skin.  Niacinamide can improve skin's elasticity, dramatically enhance its barrier function, help erase discolorations, and revive skin's healthy tone and texture.

  • Apply Niacinamide topically has been shown to benefit skin color,  decrease melanin synthesis, suppresses hyper-pigmentation, and decrease  inflammation and itching.
  • It has been shown to increase ceramide and free fatty acid  levels in skin, prevent skin from losing water content, and stimulate  microcirculation in the dermis
  • It also has a growing reputation for being able  to address skin discolorations (often in tandem with other proven  skin-lightening agents such as vitamin C and glucosamine) and to reduce acne.
  • The biochemical effects of Niacinamide is to increase synthesis of collagen  and to increase ceramide and free fatty acid  levels in skin,
  • Topical application of Niacinamide also decreases UV-induced skin cancers and  prevented immuno suppression by UV irradiation.
  • It  definitely belongs on the A-list of great skin-care ingredients regardless of  your skin-care concern. 
N-Acetyl Glucosamine (NAG)
  • Increases hyaluronic acid production in the skin
  • Repairs and treat sun damage
  • Reduces the appearance of wrinkles
  • Accelerates wound healing
  • Reduces trans-epidermal water loss
  • Improves skin tone
  • Improves barrier function
  • Reduces hyperpigmentation
  • Improves skin hydration
NAG has been shown to reduce hyperpigmentation and can be combined with  niacinamide to further increase its ability to reduce hyperpigmentation. One  study showed that a formulation of 4% niacinamide and 2% NAG significantly  reduced the appearance and amount of hyperpigmentation of age spots and uneven  skin pigmentation. Another eight week, double blind study showed a reduction in  facial hyperpigmentation using NAG alone. NAG inhibits the glycolysation of pro-tyrosinase,  which results in the reduction of melanin in the skin.

A similar study using Niacinamide and NAG on women 35 to 60 showed an increase  in the production of hyaluronic acid, a water binding polymer found in the skin,  which resulted in improved hydration. This increase resulted in a reduction of  appearance of fine lines, particularly around the eye area, and an increase in  the elasticity of skin.
Direction for Use
  • Recommended Usage Rate:  2% - 4%  of each  Niacinamide and NAG powder, dissolved in your  Serum, Cream or Lotion.
  • Solubility: Soluble in  water up to 20%


 

Any statements about our products have not been evaluated by the FDA.
 Our active skin care ingredients are not intended  to diagnose, treat, cure, or prevent any disease