Author Biography

Syed A. Abutalib, MD, is Co-Director of Hematology and Stem Cell Transplantation and Clinical Director of NMDP® Apheresis Center at the Midwest Branch of Cancer Treatment Centers of America, (CTCA), Part of City of Hope. Maurie Markman, MD, is President of Medicine & Science, Cancer Treatment Centers of America, Part of City of Hope. James O. Armitage, MD, is the Joe Shapiro Professor of Medicine at University of Nebraska Medical Center and has served as Dean for College of Medicine and Chairman of Internal Medicine. He is past President of both the ASCO and the ASTCT. Kenneth C. Anderson, MD, is the Kraft Family Professor of Medicine at Harvard Medical School, as well as Director of the LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center at Dana-Farber Cancer Institute. He is past President of ASH.

Table of Contents

Editors Volume 2 xii Preface xiii Author Bios xv Acknowledgement xvii Volume 1: Solid Tumors & Supportive Care Volume 1 Editors:
Syed A. Abutalib, Maurie Markman, Al B. Benson III, and Hope S. Rugo Part 1 Acute Lymphoblastic Leukemia in Adults 1 1 Prognostic Markers and Models in Acute Lymphoblastic Leukemia 3
Dieter Hoelzer 2 Acute Lymphoblastic Leukemia—Treatment and Outcomes in B-ALL 11
Vijaya Raj Bhatt, Prajwal Dhakal, and Syed A. Abutalib 3 T Cell Acute Lymphoblastic Leukemia and Acute Lymphoblastic Lymphoma 27
Syed A. Abutalib and Daniel J. DeAngelo 4 Minimal Residual Disease in Acute Lymphoblastic Leukemia 51
Caner Saygin, Sarah Monick, and Wendy Stock 5 Hematopoietic Transplantation and Cellular Therapy in Acute Lymphoblastic Leukemia 63
Yael Morgenstern, Netanel A. Horowitz, and Jacob M. Rowe Part 2 Acute Myeloid Leukemia in Adults 81 6 Prognosis in Acute Myeloid Leukemia: Beyond Cytogenetics 83
Caner Saygin and Lucy A. Godley 7 Young Adults with Acute Myeloid Leukemia 93
Sangeetha Venugopal and Farhad Ravandi 8 Older Adults with Acute Myeloid Leukemia 103
Mary-Elizabeth Percival and Elihu Estey 9 Acute Promyelocytic Leukemia 113
Eytan M. Stein and Martin S. Tallman 10 Measurable Residual Disease in Acute Myeloid Leukemia 121
Marie Bill and Hans Beier Ommen 11 Hematopoietic Cell Transplantation and Cellular Therapy in Acute Myeloid Leukemia 133
Piyanuch Kongtim and Stefan O. Ciurea Part 3 Myelodysplastic Syndromes and Familial Myeloid Neoplasms 147 12 Diagnosis of Myelodysplastic Syndromes 149
Jay Yang, Vijendra Singh, Ali Gabali, and Charles A. Schiffer 13 Treatment of Myelodysplastic Syndromes 165
Rami S. Komrokji 14 Hematopoietic Cell Transplantation and Cellular Therapy in Myelodysplastic Syndromes 179
Ibrahim Yakoub-Agha 15 Familial Myeloid Neoplasms—When to Suspect and What to Do? 191
Ryan J. Stubbins, Amy M. Trottier , Simone Feurstein, and Lucy A. Godley Part 4 Myeloproliferative Neoplasms 211 16 Chronic Myeloid Leukemia: Chronic Phase Disease 213
Jerald P. Radich 17 Chronic Myeloid Leukemia: Advance Phases of the Disease 221
Michael J. Mauro 18 Chronic Myeloid Leukemia: Treatment Safety During Reproductive Age and Pregnancy 229
Michael J. Mauro 19 Chronic Myeloid Leukemia: Cessation of Therapy 235
Anand A. Patel and Richard A. Larson 20 Hematopoietic Cell Transplantation in Chronic Myeloid Leukemia 243
Jerald P. Radich 21 Polycythemia Vera 255
Prithviraj Bose and Srdan Verstovsek 22 Essential Thrombocythemia 265
Paola Guglielmelli and Alessandro Maria Vannucchi 23 Primary Myelofibrosis 275
Douglas Tremblay, Sangeetha Venugopal, John Mascarenhas, and Ruben Mesa 24 Hematopoietic Cell Transplantation and Cellular Therapy in Primary and Post ET/PV Myelofibrosis 287
Jerry Luo, Irum Khan, and Damiano Rondelli 25 Chronic Myelomonocytic Leukemia 305
Mrinal M. Patnaik 26 Eosinophilic Myeloproliferative Disorders 315
Jason Gotlib Part 5 Chronic Lymphocytic and Other Leukemias 331 27 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma 333
Jayastu Senapati, Nitin Jain, and Susan O'Brien 28 Hematopoietic Cell Transplantation and Cellular Therapy in Chronic Lymphocytic Leukemia 345
Ajay Major, Michael R. Bishop, and Peter A. Riedell 29 Prolymphocytic Leukemia 357
Dima El-Sharkawi and Claire Dearden 30 Hairy Cell Leukemia 371
Justin M. Watts and Martin S. Tallman Part 6 Hodgkin Lymphoma 385 31 Classic Hodgkin Lymphoma 387
Christopher R. D'Angelo, James O. Armitage, and Nancy L. Bartlett 32 Nodular Lymphocyte-Predominant Hodgkin Lymphoma 401
Dennis A. Eichenauer 33 Hematopoietic Cell Transplantation and Cellular Therapy in Hodgkin Lymphoma 408
Narendranath Epperla, Alex F. Herrera, and Matthew Mei Part 7 Non-Hodgkin's Lymphomas 417 34 Pitfalls in the Diagnosis of Non-Hodgkin's Lymphomas 419
Carmen Barcena and Laurence de Leval 35 Follicular Lymphoma 435
Danielle Wallace, Nancy Torres, and Carla Casulo 36 Mantle Cell Lymphoma 447
Christina Poh and Stephen D. Smith 37 Marginal Zone Lymphoma 455
Erin Mulvey, Wayne Tam, and Peter Martin 38 Hematopoietic Cell Transplantation and Cellular Therapy in Indolent Non-Hodgkin's Lymphomas 471
Karthik Nath and Craig S. Sauter 39 Diffuse Large B Cell Lymphoma 485
Alessia Castellino and Grzegorz S. Nowakowski 40 Hematopoietic Cell Transplantation and Cellular Therapy in Diffuse Large B Cell Lymphoma 499
Shreya Desai, Syed Maaz Tariq, Arjun Patel, Istvan Redei, and Syed A. Abutalib 41 Primary Mediastinal Large B Cell Lymphoma 515
Alessandro Broccoli and Pier Luigi Zinzani 42 Double-Hit and Double-Expressor Lymphomas 525
David A. Russler-Germain and Brad S. Kahl 43 Transformed Lymphoma 539
Frederique St-Pierre and Jane N. Winter 44 Burkitt Lymphoma 555
Mark Roschewski and Wyndham Wilson 45 Primary and Secondary CNS Lymphomas 563
Leon D. Kaulen, Nicholas A. Blondin, Fred H. Hochberg, and Joachim M. Baehring 46 HIV-Associated Lymphoma 579
Elif Yilmaz and Kieron Dunleavy 47 Waldenström's Macroglobulinemia 589
Morie A. Gertz 48 Primary Cutaneous Lymphomas 599
Nicholas A. Trum, Jasmine Zain, Steven T. Rosen, and Christiane Querfeld 49 Mycosis Fungoides and Sézary Syndrome 635
Robert Stuver, Alison Moskowitz, Sarah Noor, and Steven M. Horwitz 50 Peripheral T-Cell Lymphoma 647
Avyakta Kallam and James O. Armitage Part 8 Plasma Cell Neoplasms and Related Disorders 659 51 Monoclonal Gammopathy of Undetermined Significance and Smoldering Multiple Myeloma 661
Francesco Maura, Dickran Kazandjian, and Ola Landgren 52 Risk Stratification Including Measurable Residual Disease in Multiple Myeloma 673
Charalampos Charalampous and Shaji Kumar 53 Newly Diagnosed Multiple Myeloma: Transplant Eligible 687
Sagar Lonial 54 Newly Diagnosed Multiple Myeloma: Transplant Ineligible 699
Daniele Derudas and Claudio Cerchione 55 Relapsed/Refractory Multiple Myeloma 713
Neha Korde and Saad Z. Usmani 56 Light-chain (AL) Amyloidosis 727
Vaishali Sanchorawala 57 Bispecific T Cell Engager and Cell Based Immune Therapy in Multiple Myeloma 739
Meera Mohan, Parameswaran Hari, and Saurabh Chhabra Part 9 Special Issues in Neoplastic Hematology and Cellular Therapy 751 58 Treatment of Lymphomas During Pregnancy 753
Kieron Dunleavy, Emanuele Zucca, and Fedro A. Peccatori 59 Complications and Management of CAR T Cell Therapy 767
Radowan A. Elnair and Matthew A. Lunning 60 Acute Graft-versus-Host Disease 781
Aaron Etra, Uroosa Ibrahim, Jacques Azzi, and John E. Levine 61 Chronic Graft-versus-Host Disease 793
Andrew Trunk and Daniel R. Couriel Index 809

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