Publisher Description

Coumarins: Biology, Applications and Mode of Action predominantly focuses on the parent compound, coumarin, and its main metabolite in humans, 7-hydroxycoumarin. It describes in detail every facet of these compounds including history, toxicology, chemistry, metabolism, analysis, clinical, veterinary and other applications, their roles as immunomodulatory agents and speculates on their mode of action.

Back Cover

Coumarins are a group of compounds that have important roles as food constituents; as anti-oxidants, stabilisers, and immunomodulatory substances; as fluorescent markers for use in analysis, in lasers and in clinical use. Coumarins: Biology, Applications and Mode of Action predominantly focuses on the parent compound, coumarin, and its main metabolite in humans, 7-hydroxycoumarin. It describes in detail every facet of these compounds including history, toxicology, chemistry, metabolism, analysis, clinical, veterinary and other applications, their roles as immunomodulatory agents and speculates on their mode of action. Features include:

• New insights into mode of action of coumarins
• Comprehensive summary of new coumarin compounds
• Detailed accounts of methods used for analysis
• Applications of coumarins for diverse methods of analysis

Flap

Coumarins are a group of compounds that have important roles as food constituents; as anti-oxidants, stabilisers, and immunomodulatory substances; as fluorescent markers for use in analysis, in lasers and in clinical use. Coumarins: Biology, Applications and Mode of Action predominantly focuses on the parent compound, coumarin, and its main metabolite in humans, 7-hydroxycoumarin. It describes in detail every facet of these compounds including history, toxicology, chemistry, metabolism, analysis, clinical, veterinary and other applications, their roles as immunomodulatory agents and speculates on their mode of action. Features include: * New insights into mode of action of coumarins * Comprehensive summary of new coumarin compounds * Detailed accounts of methods used for analysis * Applications of coumarins for diverse methods of analysis This volume will be of interest to those working in biochemistry, chemistry, pharmacology, clinical sciences and toxicology.

Author Biography

Richard O'Kennedy is the editor of Coumarins: Biology, Applications and Mode of Action, published by Wiley. R. Douglas Thornes is the editor of Coumarins: Biology, Applications and Mode of Action, published by Wiley.

Table of Contents

Partial table of contents:

History of the Development and Applications of Coumarin and Coumarin-related Compounds (I. Weinmann).

The Chemistry and Occurrence of Coumarins (G. Keating & R. O'Kennedy).

Coumarin as an Immunomodulator (G. Zlabinger).

Mode of Action of Coumarin in the Treatment of Thermal Injuries (N. Piller).

The Potential Role of Coumarins in the Therapy of Prostate Cancer (J. Mohler, et al.).

Clinical and Biological Observations Associated with Coumarins (R. Thornes).

Analysis of Coumarins (D. Bogan, et al.).

Suggested Modes of Action of Coumarins and Some Comments on their Significance (R. O'Kennedy & R. Thornes).

Index.

Long Description

Coumarins are a group of compounds that have important roles as food constituents; as anti-oxidants, stabilisers, and immunomodulatory substances; as fluorescent markers for use in analysis, in lasers and in clinical use. Coumarins: Biology, Applications and Mode of Action predominantly focuses on the parent compound, coumarin, and its main metabolite in humans, 7-hydroxycoumarin. It describes in detail every facet of these compounds including history, toxicology, chemistry, metabolism, analysis, clinical, veterinary and other applications, their roles as immunomodulatory agents and speculates on their mode of action. Features include: ∗ New insights into mode of action of coumarins ∗ Comprehensive summary of new coumarin compounds ∗ Detailed accounts of methods used for analysis ∗ Applications of coumarins for diverse methods of analysis This volume will be of interest to those working in biochemistry, chemistry, pharmacology, clinical sciences and toxicology.

Feature

Discusses the various uses of coumarins as anti-disease agents.

Details