Floto Venezia Slim Tuscan Red Vegetable Tanned Leather Briefcase Laptop Continental Classic Multi-Purpose Office and Travel Bag Handmade Italy Lightweight Double-Handles and Adjustable Crossbody 42" Detachable Strap. This beautiful slightly used $269.00 unisex briefcase goes from office to overnight bag to travel bag via airline, train or cruiseship. Silver-tone hardware.
Vegetable tanned leather is leather that is tanned using natural tannins from trees or other plants. The color and texture of vegetable tanned leather consists of variety of rich color tones, patterns, and depth of the color reaching the inner molecules of the leather, producing a much more natural look and has given rise to the very popular modern style known as distressed or antiqued leather. The natural tannins used in vegetable tanning bind to protein structures in the hide, stabilize its fiber structure, and prevent decay. The colors from vegetable tanning darken over time. The feel of vegetable tanned leather softens over time. Vegetable tanned leather takes 30-60 days to produce, making the products generally more expensive; it can cost around three times more than chrome or mineral tanned products. 
Here is more information directly from the Floto website:

The Venezia Slim Brief is made with vegetable tanned calfskin leather... The calfskin leather for this slim case was vegetable tanned in Tuscany to create rich color tones while the semi gloss finish helps prevent stains. Over time this leather briefcase will soften and develop a beautiful patina. Our 8 oz cotton duck canvas lining is made in South Carolina and very durable. The combination of Italian vegetable tanned leather, Italian craftsmanship, and U.S. made canvas lining make our leather briefcases beautiful, durable, and lightweight. Made in Italy.

 

12" h x 4" w x 17" l

Italian Polished Calfskin Leather

Detachable Shoulder Strap (42-48")

Brass Hardware

Durable Canvas Lining

7" x 14" Zip Sleeve / Tablet Pocket

Inside Zip Pocket

Weight 2.5 Pounds