Leiomyosarcoma
by Rosemary H. Leach
Leiomyosarcomas (LMS) are soft tissue tumours derived from smooth muscles cells, often in the uterus, retroperitoneum, skin, vessels, and bone. They are one of the most common types of sarcoma. Most leiomyosarcomas are sporadic, but may develop in the setting of genetic syndomes such as hereditary retinoblastoma and L-Fraumeni syndrome. Leiomyosarcomas may also be a result of radiation exposure; however, radiation-induced sarcomas are typically undifferentiated, fibrosarcomas or malignant peripheral nerve sheath tumors. Like other sarcomas, prognosis is worse with higher grade tumours. Although chemotherapy and radiation are sometimes used as adjuvant therapy, the mainstay of therapy, and the only chance for cure, is surgery. The management of LMS is especially complex when the tumour involves major blood vessels. This book discusses the diagnosis and treatments most effectively used for Leiomyosarcomas. It also provides insight on the specific areas that LMS is found and how it affects that area.
Hardcover
English
Brand New
Table of Contents
Preface; Surgical Management of Leiomyosarcoma Involving the Major Abdominal Vessels; Leimyosarcomas of the Genitourinary Tract; Reconstructive Challenges in Leiomyosarcoma; Diagnosis & Treatment of Leiomyosarcomas; Primary Intracranial Leiomyosarcoma; Adult Urologic Leiomyosarcomas; Cardiac Leiomyosarcoma; Cutaneous Leiomyosarcoma; Diagnosis & Pitfalls of Uterine Leiomyosarcoma; Clinical Manifestation & Imaging Diagnosis of Leiomyosarcoma; Gastrointestinal Leiomyosarcoma (GI-LMS) & GI Stromal Tumor (GIST); Primary Ovarian Leiomyosarcoma: A Very Rare Entity; Leiomyosarcoma in the Female Genital Tract: Risk Factors, Diagnosis & Treatment Options; Index.
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