Publisher Description

Tissue engineering is a multi-disciplinary field that is continually evolving and functions through the amalgamation of principles and practices derived from materials science, clinical medicine and the basic biological sciences. The goals of tissue engineering based therapies are to reconstitute the anatomic milieu and physiological function of diseased or damaged tissue in order to improve the poorly functioning target organ. With the advent of new synthetic polymers and advancements in stem cell biology, the combinatorial and/or synergistic effects of these disciplines has greatly advanced tissue engineering as a whole, particularly in the field of bladder tissue engineering. This book focuses on the current state of bladder tissue engineering with a specific emphasis on the use of autologous and allogenic cell sources, as well as biologic and synthetic matrices that influence cell growth and differentiation that can be used for future bladder tissue engineering applications.

Table of Contents

Preface; Normal Bladder Anatomy & Physiology; Etiology of the Neurogenic Bladder; Current Treatment Modalities for the Neurogenic Bladder Are Inadequate; Advances in Tissue Engineering for Bladder Regeneration; Alternate Cell Sources for Bladder Tissue Engineering; Bone Marrow Microenvironment; Msc Multipotentiality & Growth Characteristics; The Potential of MSCS in Regenerative Medicine; Bone Marrow Cells & Bladder Regeneration; Endothelial Progenitor Cells for Vascular Growth; Neural Progenitor/Stem Cells; Embryonic Stem Cells; Induced Pluripotent Stem Cells; Scaffold Material Selection: Biologics versus Synthetics/Polymerics; Controlled Delivery of Growth Factors From Scaffolds Enhances Tissue Regeneration; The Use of Nanotechnology with Self-Assembling Matrices Provides an Alternative Method of Growth Factor Delivery; Self-Assembling Nanomolecules; Pa Molecules for Tethered Growth Factor Delivery; Differentiation of Neural Progenitor Cells with Ikvav Presenting Nanofibers; Summary; Index.

Details