Virgil is traditionally ranked as one of Rome's greatest poets. His Aeneid has been considered the national epic of ancient Rome since the time of its composition. Modeled after Homer's Iliad and Odyssey, the Aeneid follows the Trojan refugee Aeneas as he struggles to fulfill his destiny and reach Italy, where his descendants Romulus and Remus were to found the city of Rome. Virgil's work has had wide and deep influence on Western literature, most notably Dante's Divine Comedy, in which Virgil appears as the author's guide through Hell and Purgatory.

Sometime after the publication of the Eclogues (probably before 37 BC), Virgil became part of the circle of Maecenas, Octavian's capable agent d'affaires who sought to counter sympathy for Antony among the leading families by rallying Roman literary figures to Octavian's side. Virgil came to know many of the other leading literary figures of the time, including Horace, in whose poetry he is often mentioned, and Varius Rufus, who later helped finish the Aeneid.

At Maecenas' insistence (according to the tradition) Virgil spent the ensuing years (perhaps 37–29 BC) on the long didactic hexameter poem called the Georgics (from Greek, "On Working the Earth") which he dedicated to Maecenas. The ostensible theme of the Georgics is instruction in the methods of running a farm. In handling this theme, Virgil follows in the didactic ("how to") tradition of the Greek poet Hesiod's Works and Days and several works of the later Hellenistic poets. The four books of the Georgics focus respectively on raising crops and trees (1 and 2), livestock and horses (3), and beekeeping and the qualities of bees (4). Well-known passages include the beloved Laus Italiae of Book 2, the prologue description of the temple in Book 3, and the description of the plague at the end of Book 3. Book 4 concludes with a long mythological narrative, in the form of an epyllion which describes vividly the discovery of beekeeping by Aristaeus and the story of Orpheus' journey to the underworld. Ancient scholars, such as Servius, conjectured that the Aristaeus episode replaced, at the emperor's request, a long section in praise of Virgil's friend, the poet Gallus, who was disgraced by Augustus, and who committed suicide in 26 BC.

The Georgics' tone wavers between optimism and pessimism, sparking critical debate on the poet's intentions, but the work lays the foundations for later didactic poetry. Virgil and Maecenas are said to have taken turns reading the Georgics to Octavian upon his return from defeating Antony and Cleopatra at the Battle of Actium in 31 BC.

John Dryden (19 August 1631 – 12 May 1700) was an English poet, literary critic, translator, and playwright who was appointed England's first Poet Laureate in 1668.  He is seen as dominating the literary life of Restoration England to such a point that the period came to be known in literary circles as the Age of Dryden. Romanticist writer Sir Walter Scott called him "Glorious John".