Cast Overview:
| Peter Dinklage | Tyrion Lannister (47 episodes, 2011-2016) | |
| Lena Headey | Cersei Lannister (45 episodes, 2011-2016) | |
| Emilia Clarke | Daenerys Targaryen (42 episodes, 2011-2016) | |
| Kit Harington | Jon Snow (42 episodes, 2011-2016) | |
| Sophie Turner | Sansa Stark (41 episodes, 2011-2016) | |
| Iain Glen | Jorah Mormont (40 episodes, 2011-2016) | |
| Maisie Williams | Arya Stark (40 episodes, 2011-2016) | |
| Nikolaj Coster-Waldau | Jaime Lannister (37 episodes, 2011-2016) | |
| John Bradley | Samwell Tarly (36 episodes, 2011-2016) | |
| Alfie Allen | Theon Greyjoy (33 episodes, 2011-2016) | |
| Aidan Gillen | Petyr 'Littlefinger' Baelish (31 episodes, 2011-2016) | |
| Jerome Flynn | Bronn (29 episodes, 2011-2016) | |
| Conleth Hill | Lord Varys (29 episodes, 2011-2016) | |
| Gwendoline Christie | Brienne of Tarth (28 episodes, 2012-2016) |