Bill the Cat twice won the National Radical Meadow Party's nomination to run for President of the United States, in 1984 and 1988, despite being dead in the first instance, and despite having a vocabulary that mainly consisted of "Aack!" He lost twice, once because of coughing up a fur ball on Connie Chung. In spite of this political affiliation, he embarked on a torrid love affair with Jeane Kirkpatrick, then was later used as the primary source for an illegal cat-sweat-based baldness cure. His brain was replaced with Donald Trump's (who had been hit with his yacht's anchor while sunbathing in New York Harbor).

The Starship Enterpoop was an ongoing gag/Star Trek parody in the Bloom County comic series, in which wheelchair-riding Cutter John would play the part of Captain Kirk, various (speaking) local fauna would be members of the crew, and all the world would be an alien stage to explore.