The wedding of the Vision and the Scarlet Witch marked a historic moment in Marvel Comics. It was the first wedding of two superheroes in the Marvel Universe and a groundbreaking event for its time.

The cover of this issue typically features the Vision and Scarlet Witch in wedding attire, and it often showcases the Avengers in action.

"Giant-Size Avengers" #4 is a highly collectible comic due to the historic significance of the Vision and Scarlet Witch's wedding. It's sought after by fans and collectors interested in key moments in Marvel's history.