10mL Genizer Jacketed Liposome ExtruderAir-Driven and Temperature-controlled
Refurnished; Fully functional; No Return; No Regulator; Gas Connection CGA580 (USA)


Description:
 
The Genizer Jacketed Liposome Extruders is compressed air-driven and temperature-controlled, from testing to manufacturing production of liposome and lipopolyplex, for drug and gene delivery. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The process is relatively gentle, exposing the formulation to moderate pressures up to 500 psi at controlled temperatures. The Genizer Jacketed Extruder offers virtually no dead-volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.
 
Application:
 
Liposome extrusion
 
Performance:
 
No dead volume
The Jacketed Extruder can control the temperature of the extrusion
 
Specifications
Catalog No.GJE-10mLGJE-100mLGJE-800mLGJE-3000mL
Sample Size10mL100mL800mL3,000mL
CoolingJacketedJacketedJacketedJacketed
Dimensions23cm×13cm×25cm23cm×20cm×32cm25cm×25cm×37cm30cm×25cm×55cm
Weight4kg7kg20kg45kg
Min. Sample Size5mL10mL120mL800mL
ApplicationLiposome formulation up to production scale
Max. Pressure80 psi-500 psi
Max. Temp.80ºC (176ºF)
Power TypeCompressed gas
Nano-membraneTrack-etched membrane
CleaningFlush to clean/CIP/SIP
SterilizationWhole unit autoclavable
 
Standard Features
Parts1) Liposome Jacketed Extruder 2) 10 pieces of 100nm membrane
Feed ReservoirTemperature-controled jacketed cylinder
Inlet Type1/4" high pressure coupling
Outlet Type1/4" high pressure coupling
Nitrogen TubingG5/8" - 14 TPI BSP inlet nitrogen high pressure soft tubing; adaptor with 3/8-inch male NPT and 1/4-inch female flare outlet
Nano Membrane100nm track-etched polycarbonate membrane
CompatibilitySome parts are compatible with Lipex in Northern Lipids
Product Material316L stainless steel, NBR  or FKM
Material StandardSanitary grade; compliant with FDA and GMP sanitary standards
Warranty1 year against any manufacturing defects
 
Option Features
DetectorPressure gauge, pressure transducer, temperature transducer
Inlet TypeTri-clamp or luer
Outlet TypeTri-clamp or luer
Nano Membrane30, 50, 80, 130, 200, 400, 800nm, 1300nm, 2μm, 5μm, 10μm, 20μm, 30μm track-etched membrane (25mm, 47mm, 90mm, 160mm, 293mm)
Multi ExtruderParallel or series connection of multi-extruder