• Product Overview

    Clinically proved to lower cholesterol†. Click below to learn more.

    Nature Made CholestOff® Plus is made with Reducol, a proprietary blend of plant-based sterols and stanols (also called phytosterols). Sterols and stanols work to help reduce cholesterol absorption and reduce LDL (bad) cholesterol in the bloodstream.

    CholestOff® Plus is an option for your cholesterol management program, along with a diet low in saturated fat and cholesterol.1 ,2 ‡ One serving of Nature Made CholestOff® Plus supplies 900 mg of plant sterols and stanols for a daily intake of 1800 mg.

    • 900 mg of plant sterols and stanols per serving
    • Clinically proven to lower cholesterol.
    • A safe and effective part of a cholesterol management program.
    • #1 Pharmacist Recommended Vitamin and Supplement Brand*

    How does it work?

    Plant sterols and stanols, also referred to as the phytosterols, are plant-derived compounds that are similar in structure to cholesterol. Plant sterols and stanols compete with cholesterol for aborption in the digestive tract. As a result, the sterols and stanols help block dietary cholesterol absorption and reduce LDL (“bad”) cholesterol.

    The dietary supplement form of phytosterols provides a convenient, easy to take supplement and offers approximately 1.8 grams (1800 mg) of phytosterols per day with a negligible amount of calories. Because many Americans consume as little as about 200 mg per day, this is the amount many Americans need to reach the 2,000 mg per day recommended by the National Institute of Health (NIH) Therapeutic Lifestyle Changes Guidelines.

    Food Sources

    Plant sterols and stanols occur naturally in small amounts in plant-based foods such as unrefined vegetable oils, whole grains, vegetables, fruits, nuts and legumes. However, in order to meet the recommended guidelines for cholesterol reduction through un-fortified food alone, one would need to consume an excessive amount (e.g. 18 apples or 20 tomatoes daily) of these foods to obtain the recommended 2000 mg of sterols and stanols.

    ‡Products containing at least 400 mg per serving of plant sterols and stanols, eaten twice a day with meals for a daily intake of at least 800 mg as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. One serving of CholestOff® Plus supplies 900 mg of plant sterols and stanols for a daily intake of 1800 mg.

    ††Sterols/Stanols are esterified with sunflower oil fatty acids.

    *Based on a survey of pharmacists who recommend branded vitamins and supplements.

    Product Dosage/Ingredient Information

    Suggested Use: Adults, take 2 softgels twice daily with water at your two largest meals.

    Ingredients: Plant Sterols/Stanols (Pine Tree), Sunflower Oil Esters, Gelatin (Porcine), Glycerin, Medium Chain Triglycerides, Rapeseed Lecithin, Water, Colors Added.

    Caution: If you are pregnant, nursing, or taking any medications, consult your physician before use.

    No Synthetic Dyes -- Color Derived from Natural Source, No Artificial Flavors, No Preservatives, Gluten Free

    Store tightly closed, in a cool, dry place, out of reach of children.

    Do not use if imprinted seal under cap is broken or missing.


    USP Verified

    Nature Made® was the first national supplement brand to have a product verified by United States Pharmacopeia (USP), and Nature Made® is the national supplement brand with the most products carrying the USP Verified Mark. USP is a scientific, nonprofit organization that has been setting federally recognized, public standards of quality for medicines, dietary supplements, and food ingredients.

    Why Nature Made

    Why Nature Made?

    Nature Made’s Commitment to your Health

    Everyone wants a firm foundation to stand upon when making decisions about their health. Since 1971, the Nature Made® brand has been dedicated to supporting your health with a wide range of high quality vitamin supplements. Because of our strong stand on quality and science for more than 40 years, Nature Made has earned recognition and trust among nutrition experts and people just like you.

    Safe and Quality Ingredients

    Nature Made products are made in accordance with strict Good Manufacturing Practice standards. Nature Made nutrition supplements are made from carefully selected ingredients from trusted suppliers. Nature Made products are guaranteed to meet high quality standards of purity and potency. When you take the vitamins behind that familiar yellow label, know that you’re taking the best for your health.

Return Policy;
Buyer is responsible for return shipping. Items must be returned in new, undamaged condition in original packaging, Please understand that shipping costs are not refundable, since they have already been paid to the shipping carrier.
Warranty; 
Items under warranty are exchanged; buyer is responsible for shipping expenses.
Hours Of Operation;
Business Hours: 8AM-4PM Pacific Standard Time Monday-Friday (Except Holidays)
Closed: Saturday-Sunday and all Holidays.
All Purchases will be shipped on the Next Business Day.