The third season of the American television medical drama
Grey's Anatomy, commenced airing on the American Broadcasting Company (ABC) on
September 21, 2006, and concluded on May 17, 2007. The season was produced by
Touchstone Television, in association with Shondaland Production Company and
The Mark Gordon Company, the showrunner being Shonda Rhimes. Actors Ellen
Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers and T. R. Knight reprised
their roles as surgical interns Meredith Grey, Cristina Yang, Izzie Stevens,
Alex Karev and George O'Malley, respectively, continuing their expansive
storylines as focal points throughout the season. Previous main cast members
Chandra Wilson, James Pickens, Jr., Kate Walsh, Isaiah Washington, and Patrick
Dempsey also returned, while previous guest-stars Sara Ramirez and Eric Dane
were promoted to series-regulars, following the extension of their contracts.