This bead and VTB21 were recently purchase from a large estate collection. I have examples of Reproductions in photo 2.

Bead Size for VTB22 is 11.5mm diameter by 27 long. 

This exquisite Lewis and Clark Bead is a rare find for collectors. With origins tracing back to Venice, Italy, this single multi-colored glass bead is reminiscent of the trade beads that were popular during the African trade route. Handmade and crafted with care, this bead is a stunning example of the intricate glasswork that Venetian artisans are known for. Its unique style and design make it a perfect addition to any collection of collectibles or beads. The history and craftsmanship behind this bead make it a valuable piece that will undoubtedly stand the test of time.