Traditionally, Nu-nu, Rapé are applied by using a pipe made from bamboo or bone, which is blown through each nostril, on both sides. They can be self-administered using a V-shaped self-applicator pipe, which connects the mouth to the nostrils. Alternatively, the can be administered by another person using a blow pipe, which connects the blower?s mouth to the other person?s nostrils. The self-applicator pipe is known as ?Kuripe?, and the blow pipe is know as a ?Tepi? in the Brazilian tradition.

General suggestion is to use a pea sized amount (50% for each nostril) of medicine for beginners, and dosage can be increased after prolonged use of a specific Rapé. Also, it is suggested that you use them within a quiet sacred space without any interruptions ? sitting upright, either cross-legged or in a chair with eyes closed after application. Also, suggested slow breathing after application through the mouth/nose is very important.