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Description: Science-Based Nutrition™ Helps Support Mood and Neural Function Helps Support Joint Comfort and Mobility Helps Support Liver Health and Detoxification Vegetarian Dietary Supplement Non-GMO / Gluten Free / Soy Free Formulated with Disulfate Tosylate Doctor's Best utilizes only the highest quality Italian Soloesse® SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our Double-Strength SAM-e 400 contains 400 mg of active Soloesse® SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving. Doctor's Best SAM-e helps replenish your SAM-e levels and promote a healthy mood. SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody. Supplementing with SAM-e Soloesse® Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate bio-chemical activity in the human body. SAM-e and Mood and Cognitive Function SAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function. SAM-e and Joint Function In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue. SAM-e and Liver Function SAM-e helps support healthy levels of glutathione, a critical anti-oxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health. Double Strength SAM-e is sealed in blister packs for freshness and stability.


Suggested Use: Adult Use: Take 1 tablet daily between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.


Other Ingredients: Microcrystalline cellulose, magnesium silicate, stearic acid, magnesium stearate (vegetable source), flake shellac dewaxed, magnesium hydroxide, glycerol, silica, arginine base, sodium alginate, calcium oxide.


Warnings: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people. Store product in a cool, dry place.


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Supplement Facts: Serving Size: 1 Tablet Servings Per Container: 60 Amount per serving% Daily Value SAM-e ( S-Adenosyl Methionine disulfate p-toluensulfonate)400 mg† † Daily Value not established.