Adventure comedy sequel starring Ben Stiller, Robin Williams, Amy Adams, Owen Wilson, Hank Azaria, Bill Hader, Ricky Gervais and Steve Coogan. Stiller reprises his role as Larry Daley, the hapless security guard who encounters living and breathing museum exhibits. This time round, the Museum of Natural History has been closed for renovations, and the museum pieces moved into federal storage at the Smithsonian Institution in Washington, where the collection includes artefacts associated with many of the great figures of American history including Theodore Roosevelt (Williams), Amelia Earhart (Adams), General Custer (Hader) and Al Capone (Jon Bernthal). Larry must infiltrate the museum's tight security to rescue Jedediah (Wilson) and Octavius (Coogan), who have been shipped there by mistake.