On July 14, 1941, she married orthodontist Dr. Eugene "Jimmy" Farber, DDS, and moved with him to Los Angeles. After the Japanese attacked Pearl Harbor in December of that same year, her husband joined the US Air Force as a dentist. She accompanied him to his postings at Hamilton Air Force Base in Northern California, and at Tonopah Army Air Field (now known as Tonopah Air Force Base in Nevada. There she taught painting to the officers' wives and was fascinated by the landscape there, painting her "Two Women of Tonopah." She also painted her "Tonopah Laundry" oil focusing on the migrant women laborers.
After the war, they returned to Los Angeles, where her husband started a practice in Beverly Hills, and they raised two children. A number of her cubist style portraits of women were painted after the war, such as "Lady With Hat."
In the 1960s Gladys Aller, now known as Gladys Farber, became politically active, starting with "SOS - Stamp Out Smog" which led to the Clean Air Act. She was one of the original members of Women Strike for Peace working for nuclear disarmament and the Test Ban Treaty. She helped organize, and traveled on, a trip to the Soviet Union in the midst of the Cold War which they called "Women's Peace Plane to Moscow" in 1963. She subsequently became active in the anti-Vietnam War movement.
Artistically, in the 1950s and 1960s, her work moved away from figurative watercolors and oils and towards abstract expressionism from the earlier influences of the Ashcan School, the Southern California watercolor school, Diego Rivera and the Mexican Mural Movement, and German Expressionism.She worked in the studio of LA artist Sueo Serisawa. A close group of women painters gathered in that studio in the 1960s, often combining art with politics. Mary Clarke, Lucy Adelman (who was later one of the founders of the Womanspace Gallery and subsequently the ArtSpace Gallery), and Wallace Albertson were some of the other painters in the group.