In iconography, Saint Mary of Egypt is depicted as a deeply tanned, emaciated old woman with unkempt gray hair, either naked or covered by the mantle she borrowed from Zosimas. She is often shown with the three loaves of bread she bought before undertaking her journey into the desert.

Her feast day is kept by the Orthodox according to the Fixed Cycle on April 1. On the Moveable Cycle, the Orthodox Church also commemorates her on the fifth Sunday of Great Lent, on which day it is customary for the priest to bless dried fruit after the Divine Liturgy. The Life of St Mary, by Saint Sophronius, is appointed to be read during the Matins of the Great Canon of Saint Andrew of Crete on the preceding Thursday.

In the Catholic Church, she is listed in the 2004 edition of the Roman Martyrology on April 1. Although she is venerated by Anglicans, Saint Mary of Egypt does not appear on Anglican Church Calendars.

In Italy, this Mary became associated with the patronage of fallen women much like Mary Magdalene, to whom similar traits were associated.