• Universal: Nispira HME filter is an inline humidification solution unit for use with ALL CPAP & BiPAP Machines and CPAP Masks. 
• Easy to Install: To install a Heat Moisture Exchanger for therapeutic use, connect the large diameter end of the HME to your mask and the smaller diameter end to your CPAP tube. Be sure both connections are full seated and secure. Your HME is now ready for use 
• Replacement: HME Filters should be changed about once a week for best results. 
• Storage: When not in use HMEs should be stored a sealed plastic bag (i.e. a ZipLock). The HME will immediately begin to collect moisture and humidity when exposed to air. 
• A pack of 12 filters included. Quality meets or exceeds leading national brand