Propolis is created by bees from the natural resin produced by trees as part of their defence system. Honeybees collect the resin, mix in beeswax and enzymes, and use it to protect the hive.ComvitA� Propolis contains a range of bioflavonoids. ComvitA� Propolis Oral Spray contains 10% MGO 263+ (UMF�10+) Manuka Honey. Manuka Honey is gaining worldwide recognition for its unique naturally antibacterial properties.