What is it: Paula's Choice Clinical 1% Retinol Treatment is a lightweight, creamy lotion containing 1% retinol to help reduce the appearance of the signs of aging. Who is it for: Clinical 1% Retinol Treatment is for anyone concerned with the appearance of the signs of aging. Why is it different: Clinical 1% Retinol Treatment is formulated with licorice, oat, burdock, willow bark, vitamins C and E, and retinol. It features Paula's delivery system in a smoothing, hydrating lotion base. How do I use it: Limit initial use to three times per week; gradually increase frequency to every other night, then finally every evening as tolerated. Apply a pea-sized amount of Clinical 1% Retinol treatment to face, neck, and chest after cleansing and/or toning (sold separately). Avoid the lips, eyelids, and immediate eye area. Can be used on the perimeter of the orbital bone, if desired. Follow with eye cream and moisturiser, as needed.