Savage She-Hulk #1, published by Marvel Comics in February 1980, is the first appearance of She-Hulk (Jennifer Walters). The comic features the origin story of She-Hulk and briefly retells the origin of the Hulk (Bruce Banner).

Here's a breakdown of the key events in the comic:

Jennifer Walters, a lawyer and Bruce Banner's cousin, is critically injured by a mob hitman.

With no other options, Bruce Banner gives her a blood transfusion of his gamma-irradiated blood to save her life.

The gamma radiation has a different effect on Jennifer than Bruce, transforming her into the She-Hulk whenever she gets angry or agitated.

Unlike her cousin, She-Hulk retains her intelligence and personality in her Hulk form.

Additional details:

The comic was written by Stan Lee with art by John Buscema and Chic Stone.