BelloCell -500 Cell Culture Bottle. High Cell Density (3~5 x 10(9) Cells/Bottle)Capable of Harvesting Cells and Cell Components Ability to Sample Carriers for Cell Count Applicable for both Serum-Free and Serum-Containing Media Applicable for most Adherent Cells Super Low Shear Oxygen Limitation Plug-and-Play Pre-Sterilized, Ready-to-Use, Disposable BelloCell-500 was the first bottle available to the market, introducing the new concept of tidal flow for high-density cell culture. The simple design combines multiple functions of a mixer, oxygenator, and a large growing surface to achieve a high density of cells. The BelloCell-500 provides unlimited oxygen during culture with relatively gentle movement of the culture medium. Porous carriers are packed in the bottle that provides 15,600 cm2 surface area for cell growth. Its space and labor savings are the most notable features. One BelloCell-500 is equivalent to dozens of roller bottles, and occupies only 1/20th the space and labor. It is the most user friendly tool for laboratory researchers. Made in Taiwan.