Muira puama is believed to be a gentle tonic that strengthens, nourishes and restores the health of the central nervous system. As such, the herb has been used in stress management, mild cases of nervous exhaustion, and depression. It is also thought to relieve neuromuscular weakness, nerve pain and physical and mental fatigue.

Muira puama is believed to benefit women's reproductive health and specifically alleviate menstrual cramps and premenstrual syndrome (PMS).

Muira puama is thought to be a tonic for overall good health, ameliorating a weak constitution. It is also believed to stimulate gastrointestinal function and relieve gastrointestinal disorders, including dyspepsia and ulcers. There are also assertions that the herb helps to stimulate the circulatory system, and perhaps that is the reason why it has been used in many South American herbal blends for male pattern baldness. In 2003, Brazilian researchers reported that in lab tests the herb facilitated memory retrieval and may be beneficial for Alzheimer's patients - perhaps, again, a result of circulatory improvement.

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