Amazing Spider-Man #45  (Marvel Comics 1963 Series) in Fine Condition.

Cover by John Romita Sr.. 

The third appearance of the Lizard in Spidey Smashes Out!, script by Stan Lee, art by John Romita Sr.; 

The Lizard heads to Dr. Connor's lab to find a formula to transform reptiles into his personal army; 

Aunt May worries about Peter; The Lizard and Spider-Man battle aboard a train. 

Reprinted in Marvel Tales # 185.

Comes Bagged and Boarded.