Shipping discount for multiple items – Only €1 extra per product - Just “Request Total”

-Minimize wrinkles due to the action of many different anti-wrinkle ingredients with different modes of action (see below what each ingredient does as there are so many actives in this cream).

-Increase Collagen production and skin thickness which will plump the skin and make it more youthful. This is also achieved by the action of different ingredients; Matrixyl, Pepha Tight, Syn-Coll, Copper peptide, Hydrolyzed Lupine peptide, Niacinamide, Vitamin C Ester etc.

-Lift, firm and tighten the skin. Eye lids will appear lifted because of different ingredients working both long time and for immediate effect; Pepha Tight, Syn-Coll, DMAE, Vitamin C Ester and Caffeine etc.

-Reduce Puffiness & Dark Cirkles. Witch Hazel, Caffeine & Vitamin K and Cucumber oil in particular are known to produce this effect.

-Promote even skin tone, clear acne & inflamed skin. This is achieved due to the action of many different ingredients working at different levels. Most importantly the effect of DMAE (deanol), Vitamin C Ester, R-ALA, Niacinamide, Aloe Vera and many healing and anti-inflammatory ingredients and oils (see action of each ingredient below).

-Promote Intense Hydration due to Hyaluronic Acid, Aloe Vera, Squalane, Vegetable Glycerine, Kokum Butter, Cucumber Oil, Argan oil and the unique combination of oils and butters.

-Protect skin from aging through free radical damage due to a number of very potent Antioxidants; ALA, Vitamin C Ester, Vitamin A Palmitate, Vitamin E, Idebenone and Green Tea etc.

-Minimize pores due to Hydrolyzed Wheat Proteins and ALA. 

Further below are a list of all the ingredients with more detailed information and their mode of action!

**********

Anni Mateo Anti-aging Cosmeceuticals is a new line of bioactive skin care products with a goal to offer the very best in anti-aging skin care that gives a visible and lasting impact by combining the best of Science and nature. This goal stems from my own interest in putting together a super active "All-in-One" cream that contains everything known to reduce all signs of aging, specifically wrinkles and sagging skin, but also pigmentation, dull/uneven skin and large pores. The active ingredients have to be concentrated enough to work. I have bought numerous products myself throughout the years, many of them with a lot of promising active ingredients, only to find that they did not work as they were not concentrated enough. 

As part of my goal the products have to be very affordable. This is achieved by purchasing straight from manufacturer without middle men involved and due to no expensive marketing and fancy packaging. A second goal is to offer only products with natural ingredients, free of petroleum products, parabens, silicones, fillers, synthetic perfumes, colours or harsh preservatives etc. Since the “original” Anni Mateo “All-in-One” Cream was launched, the range of Anni Mateo creams has steadily increased as I have been asked to produce creams tailored to different needs. Please check www.annimateo.com. 

Dr Eva Rosberg Cody

Some of my feedback:

Ø     A+ product, great service, my best'find' on e-bay- ever! Love it! A++++

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream (#300530417953)

Ø     This is a great item, my 2nd pot now. Does exactley what it says. Thanks

(Anni Mateo "All-in-One" Anti-aging Wrinkle/Lifting Eye DMAE Argireline Matrixyl (#300932948102)

ØDoes what is says, thought nothing would sort my stressed skin out, this has

(Idebenone-Alpha lipoic acid-Hyaluronic acid-Ester C-vit A Palmitate-MSM+PEPTIDES (#291275340381)

Ø      Thanks...Argireline really works for me. I have less lines at 52 than at 40.

("100%" Argireline anti-wrinkle Peptide Solution-ADD to ANY CREAM (#301323519218)

Ø     Love this cream,it has already improved my complexion in a week!!! Fast Shipping

(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#300609190270)

Ø     1.5 weeks & my wrinkles are on the way out! Not sticky & really effective. A++++

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Argireline DMAE Matrixyl (#300739475576)

Ø     pharma quality at bargain prices! GREAT PRODUCT!
(Anti-aging Multi Peptide Serum Wrinkle Repair/Skin Firming/Scar Healing Copper p (#301052279421)

Ø     exellent cream the best ive used 2 date exellent service very fast delivery

(Clearing Marine Detox Cream Natural Anti-aging/inflammatory Acne Rosacea Eczema (#291179748421)

Ø     I love this cream. The texture of my skin has really improved
(Argireline-Matrixyl-Pepha Tight-Syn-Coll-ALA-Deanol-MSM-CoQ10-HA-CLA-beta Glucan (#300922533195)

Ø     My eyes look at least five years younger after 2 months use.

(Anni Mateo "All-in-One" Anti-aging Wrinkle/Lifting Eye DMAE Argireline Matrixyl (#300932948102)

Ø     Waited a few weeks to post -- great cream! Love the way my skin looks & feels!

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Argireline DMAE Matrixyl (#300608365358)

Ø     this is my second jar, really works and last a long time

(Anti-aging Apple & Tomato Antioxidant Cream Botopical Lupine peptides Alpha LA (#300876423203)

Ø     I love this product! AMAZING! Will be a repeat customer :)

(Anni Mateo"All-in-One" Anti-aging Wrinkle/Lifting Cream Argireline DMAE Matrixyl (#301181702683)

Ø     I love this cream. The texture of my skin has really improved.
(Argireline-Matrixyl-Pepha Tight-Syn-Coll-ALA-Deanol-MSM-CoQ10-HA-CLA-beta Glucan (#300922533195)

Ø     many thanks lovely soothing oil feels great on my skin

(Anni Mateo Luxury Anti-aging Tinting super-Hydrating FACIAL OIL ALL SKIN TYPES (#291162586644)

Ø     WOW!!! Used this for 3 days, can see big difference. Trust this seller 5 stars
(Anti-aging Wrinkle/Lifting Cream Firming/Large Pores/Dark Circles/Age Spots (#301206248948)

Ø     5 star seller super fast delivery love it will be back thank you so much
(Argireline-Matrixyl-Pepha Tight-Syn-Coll-ALA-Deanol-MSM-CoQ10-HA-CLA-Beta glucan (#301166233202)

Ø     Fast international delivery! Cream realy works! My skin is happy! Thanks
(Argireline-Matrixyl-Pepha Tight-Syn-Coll-ALA-Deanol-MSM-CoQ10-HA-CLA-Beta glucan (#291088985982)

Ø     Great innovative company, lovely product A+++ seller

(Anti-aging Wrinkle/Lifting Cream Firming/Large Pores/Dark Circles/Age Spots (#301206248948)

Ø     Thank you. I am very pleased with these creams, high quality and effect!

(HydroHeal Intense Anti-aging Acne Beta-Glucan Allantoin Argan oil Hyaluronic aci (#301229723191)

Ø     Item so far is brilliant
(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#301127397178)

Ø     Very nice cream, asorbs easily and good value, great transaction
(Anti-aging Wrinkle/Lifting Eye Cream Argireline Matrixyl Syn-Coll Copper peptide (#301127671797)

Ø     excellent service! really liked the note included explaining about the product!
(Anni Mateo "All-in-One" Anti-aging Wrinkle/Lifting Eye DMAE Argireline Matrixyl (#301119499372)

Ø     Another great transaction ! Many thanks, I'll be back for more. 5*
(Anni Mateo Luxury Anti-aging Tinting super-Hydrating FACIAL OIL ALL SKIN TYPES (#301089628356)

Ø     This product is brilliant!!!! Thank yo so much.
(Anni Mateo "All-in-One" Anti-aging Wrinkle/Lifting Eye DMAE Argireline Matrixyl (#291075290401)

Ø     Tremendous customer service ,really cares your happy.Highly recommended.
(Anni Mateo"All-in-One" Anti-aging Wrinkle/Lifting Cream Argireline DMAE Matrixyl (#291055873617)

Ø     A great seller, would absolutely recommend...I'll be back for more ! A +++++
(Anni Mateo Anti-Aging Wrinkle Cream ALL NATURAL Argireline Matrixyl CoQ10 CLA (#301042857581)

Ø     Love it !!! Thank you for sending so quickly
(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Argireline DMAE Matrixyl (#291015774711)

Ø     thanks for my favorite cream.your products are super
(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Argireline DMAE Matrixyl (#300982326185)

Ø     Very impressive customer care and efficient product, many thanks :o)
(Anti-aging Multi Peptide Serum Wrinkle Repair/Skin Firming/Scar Healing Copper p (#290985806271)

Ø     Love it !! Awesome customer service! This seller really cares that your happyl
(Anni Mateo Luxury Anti-aging Tinting super-Hydrating FACIAL OIL ALL SKIN TYPES (#290973448182)

Ø     This is a great item, my 2nd pot now. Does exactley what it says. Thanks
Anni Mateo "All-in-One" Anti-aging Wrinkle/Lifting Eye DMAE Argireline Matrixyl (#300932948102)

Ø     Great Seller. Amazing communication, seller offers good advices, Good products.
(Anni Mateo Anti-Aging Wrinkle Cream ALL NATURAL Argireline Matrixyl CoQ10 CLA (#300920096570)

Ø     This was my second jar. now buying the third!
(Argireline-Matrixyl-Pepha Tight-Syn-Coll-ALA-Deanol-MSM-CoQ10-HA-CLA-beta Glucan (#300879503780)

Ø     Fabulous product, gr8 packaging, fast despatch highly recommended seller.
(Anni Mateo HydroHeal Intense Anti-aging Acne Beta-Glucan Allantoin Argan Oil (#300917988642)

Ø     Really good seller and even better cream>is really so good like everybody wrote

(Anni Mateo HydroHeal Intense Anti-aging Acne Beta-Glucan Allantoin Argan Oil (#300813879868)

Ø     Just want to let you know that i've recevied the cream and let me tell you, it's amazing! it is absolutly brilliant 

to be use under make up, i got oily skin but no oil all day and keep my make up fresh with a healthy sheen 

look! it's really hyrating without any greasy heavy feeling.  i do found my face is lifted after the first application.  

Thank you very much, i will keep on using it!  Yan

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream)

Ø     Excellent seller, great packaging and instructions, can't wait to see results A+

(100% Matrixyl Anti-Wrinkle Solution-ADD to ANY CREAM (#300540166821)

Ø     super product...does what it says on the tin...many thanks.

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Argireline DMAE Matrixyl (#300622430204)

Ø     Was getting a turkey neck & this oil has cured it! The tint is no problem. :)

(Anni Mateo Luxury Anti-aging Tinting super-Hydrating FACIAL OIL ALL SKIN TYPES (#300724989761)

Lovely seller as always, great cream, perfect thank you xx

(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#300731787086)

Ø     Fast shipping. Excellent real product. Honest seller. will purchase again!

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Argireline DMAE Matrixyl (#300716040448)

Ø     great product at a good price and fass delivery,this is a good seller THANK YOU.

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Pepha Tight Syn-Coll ALA (#300621101335)

Ø     the product is great, and the product quickly became a destination.

(Natural Bioactive PORE MINIMIZING Face Cleanser Wash SLS/paraben Free (#300717172477)

Ø     love this cream - will definitely be back for more - thank you

(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#300701602597)

Ø     Great & lovely seller as always, wonderful cream that I couldn't be without x x

(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#300701602597)

Ø     This cream is fantastic, very soothing, calming and clearing for eczema, thanks

(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#300686985732)

Ø     Perfect seller and transaction: lighting fast, good quality and communication!

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Pepha Tight Syn-Coll ALA (#300700600490)

Ø     Amazing Ebayer!! Fast shipping, good quality natural products, will buy again!!!

(Anni Mateo Natural MagaLip Stick Plumper Balm Marine Filling Spheres/Peptides (#300746370816)

Ø     2nd purchase of item. Thank you

(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#300716040311)

Ø     Fast shipping. Quick communication. Price bargain for a fantastic cream. AAA++++

(Anni Mateo HydroHeal Intense Anti-aging Acne Beta-Glucan Allantoin Goats Milk (#300677518550)

Ø     Kindest seller; eager to assist with usage instructions;great communication!

(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#300670301490)

Ø     1st class service, A+ product, fast delivery, highly rec. to all! A++++++

(Anni Mateo "All-in-One" Anti-aging Wrinkle/Lifting Eye (#300529265834)

Ø     Great communication!!!!!!! Love it!!!!!

(Anni Mateo Anti-Aging Wrinkle Cream ALL NATURAL Argireline Matrixyl CoQ10 CLA (#300635730874)

Ø     The eye cream is gorgeous! So little is needed, it does tingle a little, but actually that's a nice sensation! I could feel 

a slight lifting effect, then just a lovely comfortable nourished feeling.

Now onto the face cream. It's packed to the brim! Smells lovely. More tingling, which is invigorating, 

and them that lovely, almost 'full-up' feeling when you just know you've put enough on your face & neck and any 

more would be a waste! It feels wonderful on the neck. I do have those circle things, but the cream 

seemed to wipe them out, or at least that's how it felt!

So, in my humble opinion? I'll be sticking with your range because I trust it, you very obviouly know what you're doing 

and it feels wonderful on my skin. Another thing, I don't wear much make-up, but my skin feels so good at the moment that 

I can imagine with continued use of such high quality face creams, a person would need even less. 

Congratulations, you have a wonderful range and thank you for sharing it with us!  Marie x
(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Face and Eye Cream)

Ø     LOVE THIS PRODUCT....WILL BE BACK....

(Luxury Anti-aging/tinting/superhydrating FACIAL OIL (#300547211539)

Ø     great product,fast delivery,good price.thank you.

(Anni Mateo "All-in-One" Anti-aging Wrinkle/Lifting Eye (#300560394523)

Ø     love it thanks

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Pepha Tight Syn-Coll ALA (#300700600490)

Ø     Very fast shipping. Non gresy. Thank you.

(Anni Mateo "All-in-One" Anti-aging Wrinkle/Lifting Eye (#300518155750)

Ø     Fast delivery great communication this is my 2nd pot thanks A++++++++++++

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream (#300508446741)

Ø     lovely cream thank you

(Anni Mateo "All-in-One" Anti-aging Wrinkle/Lifting Eye (#300496398112)

Ø     Excelent first class products and service. Will use again.Thanks.

(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#300716040311)

Ø     Product actually works, a great value, & lightning shipping! Would order again.

(Anni Mateo "All-in-One" Anti-aging Wrinkle Cream (#300488898022)

Ø     Excellent! Good price, communication and superfast delivery! HIGHLY RECOMMEND!

(Anni Mateo Anti-aging Multi Peptide Serum Wrinkle Repair/Skin Firming/Scar Heal (#300719631897)

Ø     ABSOLUTELY THE BEST!!!! 10 STAR SELLER!!!! SUPER FAST SHIP!!!! AWESOME SELLER!!!

(Anni Mateo HydroHeal Intense Anti-aging Acne Beta-Glucan Allantoin Goats Milk (#300692393796)

Ø     Genial

(Anni Mateo Anti-aging Multi Peptide Serum Wrinkle Repair/Skin Firming/Scar Heal (#300691133980)

Ø     Perfect seller and transaction: lighting fast, good quality and communication!

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Pepha Tight Syn-Coll ALA (#300700600490)

Ø     Great product at good price. Will be back x

(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#300677517410)

Ø     A really nice ebayer. Thank you xx

Ø     very good communication, good p&p, would buy again from this seller thankyou.

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Argireline DMAE Matrixyl (#300677519421)

Ø     Kindest seller; eager to assist with usage instructions;great communication!

(Clearing Marine Detox Cream ALL NATURAL BIOACTIVE Anti-aging Acne Rosacea Eczema (#300670301490)

Ø     Perfect seller and transaction: lighting fast delivery and excellent quality!

(Anni Mateo All-in-One Anti-aging Wrinkle/Lifting Cream Argireline DMAE Matrixyl (#300670301300)

Ø     Will definitely buy from again! Thanks!

(100% Argireline anti-wrinkle solution-ADD to ANY CREAM! (#300485016407)

Ø     Good ebayer vfast delivery would use again wife very pleased THANK YOU AAA Plus

(Anti-aging Wrinkle Cream-ALL ANTI-AGING ACTIVES (#300465742269)

Important info

Due to the content and concentration of certain actives in the cream it might slightly itch or tingle a few minutes after application, but should be continued and the skin will get used to it. Most of the ingredients in this cream are actually food grade. 

Gently pat a small amount of cream with one or two fingers around the eye area, never rub or pull the sensitive skin around the eyes! The cream is slightly yellowish as it contains Idebenone (Coenzyme Q10 evolved) and Sea Buckthorn oil which is orange/reddish. It is a very light cream which will last long. It is intensely hydrating without leaving any greasiness, perfect for both night and day, for men and women. It smells wonderful due to natural ingredients such as Orange oil and Cupuacu butter. 

Due to lack of availability of non-harsh natural/suitable sun protection factors Anni Mateo Anti-aging Wrinkle/Lifting Eye Cream only has a SPF of ~5. Therefore, if out in the sun, use additional sun cream. Please note, about 0.5% of people can get an allergic reaction to Alpha Lipoic Acid. To avoid this, apply cream to your underarm before using it on the face. If redness occurs you might not tolerate the cream in which case you can send it back for a full refund. 

This cream will do what is says and you should notice a difference at the end of one jar, which will be more and more pronounced with continued use as the ingredients work over time, e.g. for Collagen production. You should, however, notice a small difference in expression wrinkling and lifting of eye lids within a few days already.

What exactly do the ingredients do?

*Argireline: Argireline mimics the actions of Botulinum by relaxing muscle contractions that create wrinkles. It is a peptide (formerly named acetyl hexapeptide-3, now acetyl hexapeptide-8 that works by inhibiting the release of neurotransmitters (inhibits SNARE complex formation and catecholamine release) when applied to the skin and thus relaxes facial tension leading to the reduction in facial lines and wrinkles with regular use. It has a demonstrated effectiveness against existing wrinkles and the development of new wrinkles with regular use. In clinical studies of twice-a-day treatment, the severity of wrinkles around the eyes decreased to ~30% following 30 days of treatment. Argireline is completely non-toxic, safe and has no side effects.

*Matrixyl: Matrixyl is the trademark name for palmitoyl pentapeptide-3, one of the powerful peptides found in the latest generation of high-end anti wrinkle skin care products. Matrixyl works at the DNA Level to stimulate the very factors in the skin which we lose as we grow old, collagen and fibronectin. The loss of collagen is what leads to thinning of the skin and the wrinkling that we associate with aging skin. Matrixyl helps to counteract this natural part of the aging process, and immediately initiate the REVERSAL of the signs of aging. Over six months, a clinical trial revealed that Matrixyl temporarily produced “a highly significant reduction in the deep and moderate wrinkles”. In fact, researchers documented changes as high as 68% (Matrixyl® 1999). Active ingredient in Strivectin™ line.

*Pepha Tight: Pepha-Tight is a registered trademark of Pentapharm Ltd. Pepha Tight is a unique skin tightener, consisting of purified algae extract combined with a fraction of polysaccharides. Several studies have proved it provides immediate tightening to the skin as well as a long term tightening effect through the strengthening of skin's connective tissue. It protecting the skin cells from oxidative stress and stimulates the formation of collagen and supports the enhancement of the connective tissue. The main constituents are polysaccharides, amino acids and vitamins. It contains Vitamin C which is an effective antioxidant and Vitamin B12, responsible for the formation of cells.

*Syn-Coll: An anti-aging product that actually stimulates the collagen synthesis in human fibroblasts. Collagen represents the main component of dermal connective tissue. Syn-coll has a unique sequence to mimic the human body's own mechanism to produce collagen. It actively compensates for any collagen deficit in the skin and makes the skin look younger. Syn-coll is an alternative to collagen injection. It has more than 350% wrinkle reduction compared to a placebo. It is clinically tested and safe.

*DMAE (deanol): DMAE improves the firmness of the skin and helps reduce the visual appearance of sagging skin. DMAE helps the body produce acetylcholine which causes the skin to firm and the muscles underneath to tone-up. It is so effective that bodybuilders have employed its abilities at competition time giving them a well chiseled appearance. When applied to the lips, DMAE helps improve blood circulation, tones the lip area, creating a fuller appearance. Hollywood has quietly been using this ingredient on celebrities for a few years now producing exceptional results. DMAE studies have shown that it reduces the accumulation of lipofuscin deposits inside cells. Lipofuscin is a cellular pigment consisting of aggregated chunks of molecular waste. It is likely that lipofuscin is not simply a by-product of aging but also contributes to the aging process.

*Nanoparticles Silicone dioxide: Millions of microscopic nano silicone dioxide particles work to conceal wrinkles instantaneously due to the light refracting properties of these prisms. A wrinkle cannot be observed by the human eye, instead what the eye sees is the shadow made by the crumple. When these tiny prisms are present, natural brightness is rebounds into a wrinkle, its darkness or shadow is diminished and the wrinkle emerges virtually gone. Used in LifeCell and Deception lines of skin care products.

*Caffeine: Caffeine is well known for its ability to increase micro circulation and reduce puffiness and is recognized as one of the best actives for dark circles and puffiness. Because of the circulation enhancement it is also well known for its ability to reduce the tissues resulting in a slenderizing effect. In a Journal of Cosmetic Medicine (2008) article it was reported to have been very effective for 80% of the subjects tested. The treatment was analyzed after 30 days with 2x daily applications of a 7% treatment. Noticeable slimming effects were noted for the lower and upper thighs as well as the hips.

*Vitamin K (Phytonadione): Vitamin K is a pro-blood clotting agent, which has also previously been prescribed by dermatologists and surgeons to relieve the symptoms of post-operative trauma. Vitamin K Creams are now widely available on the cosmetics market and claim to be able to provide some reduction of spider veins, thread veins, facial redness, bruising and circles under the eyes.

*Witch Hazel: Witch hazel’s main active constituents are: tannins (up to 10%) and volatile oils. These constituents contribute to the strong astringent effect of witch hazel. It also contains saponins and glycosides. As well as being astringent, it is anti-inflammatory, making it useful in treating oily or large-pored skin or minor pimples. Its high tannin content has a strengthening astringent effect on veins and is therefore very useful for treating varicose veins and minor capillary problems. The external skin forms a protective covering after the tannins have tightened the proteins and underlying blood vessels, thus reducing inflammation. It is mildly antiseptic and soothing. Witch hazel is also said to stimulate the formation of new epithelial cells and is often used cold or with ice to reduce the pain of sprains and athletic injuries and to reduce swollen bruises.

*GABA (Gamma Amino Butyric Acid): GABA) is a non-essential amino acid necessary for brain metabolism. It assists Niacinamide and Inositol in preventing anxiety and works in the body much like a natural tranquilizer. GABA is used in skin care to lessen the effects of wrinkles as part of an anti-aging regimen. According to recent research "the gamma-aminobutyric acid (A)-like receptor associated with skin barrier homeostasis and regulation of the receptor (could be) clinically effective for barrier dysfunctional or epidermal hyperproliferative diseases." GABA is also the active ingredient in the Freeze 24/7 line of skin care products.

*Vitamin A Palmitate (Retinyl Palmitate): Firms and boosts the skin and maintains the skins elasticity. Vitamin A nourishes the skin, counteracts inflammations and protects cell membranes and other structures within the cells from the damage caused by free radicals and in this way helps to prevent skin disorders. It also plays an important role in the functioning of the eyes and the making of new skin and mucous membranes.

*Vitamin C Ester: Vitamin C Ester is essential for the production of collagen. It also works near miracles when it comes to inflammation. Vitamin C Ester is used in treating fine lines and wrinkles on sun damaged skin, sagging skin that is losing its firmness because of damaged or lost collagen and sunburned, inflamed, or irritated skin.

*Idebenone/Coenzyme Q10: Idebenone is an evolved version of Coenzyme Q10 (CoQ10) which has been designed to be more absorbable into the human cells and thus is claimed to be far superior. Idebenone does not oxidise and create free radicals under low oxygen conditions, whereas CoQ10 does (can cause allergic reactions). Coenzyme Q10/Idebenone is plays a vital role in the production of collagen and other proteins that make up the extra cellular matrix. When the extra cellular matrix is disrupted or depleted, skin will lose its elasticity, smoothness, and tone which can cause wrinkles and premature aging. CoQ10/Idebenone help to maintain overall skin integrity and reduce the signs of aging. Topically applied, it can penetrate the cell layers of the skin and may attenuate the depth of wrinkles due to photo aging, as well as epithelial cell turnover. By functioning as an antioxidant and free radical scavenger, CoQ10/Idebenone can enhance our natural defence system against environmental stress. CoQ10/Idebenone is also useful in sun care products. Data has demonstrated a reduction of wrinkles with long-term use in skin care products. It is also called ubiquinone, the "ubiquitous quinone" because it is present in plants and animals, including the human skin. 

*Hyaluronic Acid: Hyaluronic Acid is known as the most effective moisturizer ever discovered as it absorbs between 500 and 1,000 times its weight in water. Hyaluronic Acid occurs naturally in the body and is responsible for cushioning and lubricating connective tissue. Deficiencies of Hyaluronic Acid (which generally comes with age) result in a long list of abnormalities including wrinkles in the skin. Studies have shown that supplementation of Hyaluronic Acid has an enormous ability to prevent and reverse these aging abnormalities. This powerful moisturizer and humectant for skin care formulas is also promoting the reduction of wrinkles by improving capillary health and supporting skin nourishment. Hyaluronic Acid forms a thin transparent visco elastic surface film that helps to preserve the characteristics of youthful and healthy skin: suppleness, elasticity and tone.

*Squalane: Squalane is a natural hydrocarbon and triterpene derived from a variety of plant and animal sources. It is a component of human sebum. The chemically inert nature of squalane makes it useful in cosmetic applications, where it is used as an emollient and moisturizer. Squalane in this cream is derived from Olive oil and is absorbed quickly by the skin. It is well proven that Squalane increases the spreadability of vegetable oils and fats on the skin.

*Niacinamide, Vit. B₃: Topical application of niacinamide results in increased synthesis of collagen, keratin, involucrin and flaggrin. It also decreases pruritus and inflammation, decrease oiliness, alleviate atopic dermatitis, and decrease UV-induced skin cancers. These are just a few of the beneficial effects of topical application of niacinamide to the skin.

*Oat Beta-Glucan:  Topical benefits of Beta-Glucan includes improved elasticity, skin hydration, decrease in wrinkles, dermatitis, eczema, antioxidant and free radical scavenger. Beta-glucan has been found to penetrate skin and works through the inter-cellular lipid matrix, or the cells' cement, to enter the lower levels of the skin. Another study showed beta-glucan to significantly reduce wrinkle depth and height, and reduce skin roughness in as little as ten days and thus could have a role as a non-invasive alternative to Botox. It is believed that some parties already have R&D underway in this area. More than being useful solely in cosmetics settings, however, beta glucan gains practical, medical credence from the study, which supports its use to promote wound healing and reduce scaring after surgical procedures.

*Hydrolyzed Collagen Protein: About one quarter of all of the protein in your body is collagen. Collagen is a major structural protein, forming molecular cables that strengthen the tendons and vast, resilient sheets that support the skin and internal organs. Collagen provides structure to our bodies, protecting and supporting the softer tissues and connecting them with the skeleton. As we age, our production of Collagen slows, especially if we don’t get enough Vitamin C in our diets. Many cosmetic ingredients of today are used to enhance or stimulate Collagen production, because it is a vital building block of youthful, healthy skin and hair.

*Copper peptides: GHK-Cu and certain other copper-peptides, have been found to accelerate the regeneration and repair of many types of mammalian tissues. Studies, at numerous universities and research institutes, have found copper-peptides to;  Accelerate wound repair (humans, mice, rats, guinea pigs, pigs, dogs), increase skin re-epithelialization (humans, animals), reverse aging effects on skin (humans), thickens skin, reduces small and large wrinkles, reduces blotchiness and blemishes, improves elasticity, and increases keratinocyte and fibroblast production, thickens the subcutaneous fat layer, improve skin graft transplant success (pigs), improve hair transplant success (humans). GHK analogs with fatty residue analogs increase hair follicle size, stimulate hair growth and reduce hair loss (humans, mice, rats) and increases hair growth after chemotherapy (rats), stimulate bone healing (guinea pigs, pigs, rabbits), heal injured intestinal linings (humans, rats), heal stomach ulcers (rats), block oxidative injury in tissues, restore normal function in lives damaged by toxins (rats). It also have profound anti-inflammatory actions (reduces release of oxidizing iron from ferritin, TNF-alpha, TGF-beta-1, IL-1). The actions on TNF-alpha (tumor necrosis factor alpha) are especially important since it is considered to the the "master inflammatory molecule" that plays a causative role in chronic inflammatory conditions (rheumatoid arthritis, Crohn's disease, psoriasis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, acute alcoholic hepatitis) and possibily atherosclerosis, Alzheimer’s disease, and neuropathies. Drugs that block TNF-alpha also block the other cytokines involved in the inflammation.

*D-Calcium Pantothenate (Pro vit B5, Panthenol): Application of panthenol ointment to the skin have been shown to accelerate the closure of skin wounds and increase the strength of scar tissue in animals. Adding panthenol to cultured human skin cells given an artificial wound increased the number of migrating skin cells and their speed of migration, effects likely to accelerate wound healing. This vitamin is also a component of coenzyme A (CoA), required in synthesis of fatty acids and sphingolipids. These components are of crucial importance for stratum corneum lipid bilayers and cell membrane integrity. It improves and increases the moisture-retention capacity of the skin. Dry skin stays supple and elastic for longer. It has anti-inflammatory and anti-itching effect and it stimulates skin regeneration leading to better healing of small wounds, scars and blisters.

*Vitamin E (Tocopherol): Vitamin E is a potent anti-oxidant with healing properties which also stimulates the basal layer to reproduce new cells. It is widely used by the body to protect lipids in cell membranes from oxidative damage from free radicals. It also increases the exfoliation rate and improves the skin texture.

*Vegetable Glycerine: Glycerine is a humectant (attracts moisture) and softens the skin. It is invaluable as a natural source ingredient with emollient like properties which can soften and soothe the skin and it assists the outer epidermis is retaining moisture. This helps to explain why it is one of the most popular cosmetic additives used today.

*Vitamin D₃: Vitamin D₃ regulates cell turnover. Vitamin D is formed in the body in part by interaction with sun light. This vitamin is considered to be an anti-oxidant and anti-carcinogen, and may play a role in skin pigmentation. Since it can be absorbed by the skin, applying this vitamin topically can have an effect on skin's health. 

*Green Tea Extract: Green Tea contains polyphenols, making it a strong anti-oxidant as well as it reduces inflammation. Green Tea Extract fights free radicals and thus offers protection against sun damage.

*Aloe Vera: Aloe Vera is a potent moisturizer, regenerating and healing agent. It penetrates the skin, stimulates the immune system and increases the blood circulation. It has anti-inflammatory and anti-aging effects (increases collagen synthesis and skin elasticity). The polysaccharides in Aloe Vera act as moisturizers to hydrating the skin. Secondly, aloe is absorbed into the skin and stimulates the fibroblasts to replicate themselves faster which produce the collagen and elastin fibers making the skin become more elastic and less wrinkled. Aloe also makes the surface of the skin smoother because of its cohesive effect on the superficial flaking epidermal cells by sticking them together. It also possesses the ability to interfere with the enzyme that produces melanin deposits in the skin, preventing the formation of 'liver spots', which tend to form in aging skin. It has been said that if Aloe Vera is applied regularly and for long enough it will often cause established spots to disappear. Aloe is an important source of vitamins, enzymes, sugars, anthraquinones, lignin, saponins, fatty acids, salicylic acid and amino acids.  

*Red Raspberry Seed oil: An active oil with one of the highest anti-oxidant levels due to its high broad spectrum vitamin E and essential fatty acid content. The oil is one of the best choices for anti-inflammatory skin care, astringent and softening anti-aging skin care and natural sun protection products. Very powerful in the atopic dermatitis arena and a fantastic choice for eczema and psoriasis products as well as products for burned/damaged and wrinkled kin.

*Hydrolyzed Lupine Extract: Lupine proteins help prevent collagen and elastin breakdown, aiding retention of the skins’ elasticity and promoting cellular regeneration and wound healing, making it great for mature, problem and irritated skin. Lupine proteins also help retain moisture, making it ideal for dry skin.  

*Kokum butter: Kokum butter is obtained from the seeds of the Garcinia indica tree, which grows in the savanna areas in parts of the Indian subcontinent. It has a very high content of stearic-oleic-stearic tri-glycerides which makes it a very hard, stable butter. It has a high melting point and melts on contact with the skin. It is an excellent alternative to Cocoa butter. Kokum butter has a dry, flaky feel but is quickly absorbed, non-greasy and non-comedogenic. It helps regenerate skin cells and restores the skins' elasticity. It provides hydration to the skin and hair. It also possesses anti-oxidant properties due to its high vitamin E content.

*Cucumber Oil: Cucumber is a well known remedy to help reduce dark under eye circles and skin pigmentations. It softens and hydrates the skin and is ideal for dry, sensitive and mature skin types. The oil is light, non-greasy and easily absorbed. Cucumber Oil is rich in omega 6 essential fatty acids (linoleic acid), oleic acid, palmitic acid, minerals (including potassium and silica), tocopherols and phytosterols. It can help stimulate cell regeneration and retains moisture in the skin.

Complete list of Ingredients