BI-EST 2.5 Cream is a combination of two bio-identical estrogens (Estriol USP and Estradiol USP) in a balanced ratio of 80/20 for best results. Each pump provides 2mg of Estriol USP (Wild Yam) and 0.5mg of Estradiol USP (Wild Yam) Natural Estriol & Estradiol are bioidentical to the hormones in your body. No synthetic chemicals! With added Hyaluronic Acid, Niacinamide (Vitamin B3), Allantoin, & Vitamin E. Approximately 90 pumps per bottle Menopause & Perimenopause Support May help with hot flashes and night sweats Pharmacist Formulated and Recommended No Parabens, No Soy, No GMO, and Fragrance-Free! Made in the USA Bio-identical hormone replacement therapy is the use of hormones which look exactly like the hormones your body produces naturally. These hormones are then given to patients to relieve problems associated with hormone imbalance (such as low estrogen). Biest is a perfect example of a bio-identical hormone and it is often (or should be) used to treat cases of low estrogen and menopause. Biest is a treatment used in bio-identical hormone replacement therapy (BHRT) for menopausal symptoms and anti-aging treatment. Biest is the combination of estradiol (E2) and estriol (E3). Estradiol is a fairly strong form of estrogen and estriol is a very gentle form of estrogen. Because Estriol is a gentle form of estrogen, it can balance the strong effects of estradiol. Estradiol treatment by itself can cause breast tenderness, further exacerbate fibrocystic breast disease, weight gain in the stomach, increase the risk for uterine cancers by increasing the endometrial proliferation/lining and moodiness. Estriol treatment alone is too weak for most women’s menopausal symptoms. This is why by treating with Biest, the estriol can reduce the powerful effects of estradiol but still achieve successful menopausal relief and anti-aging. The most common form of Biest is an 80:20 ratio; with estriol encompassing 80% of the dose and estradiol 20%. The flexibility of Biest f