| Saturday, July 31, 2010 | Goole A.F.C. | v | Matlock Town | Pre Season Friendly | |
| Tuesday, August 31, 2010 | Goole A.F.C. | v | Rushall Olympic | Evo-Stik League Division One South | |
| Tuesday, September 7, 2010 | Goole A.F.C. | v | Spalding United | Evo-Stik League Division One South | |
| Saturday, September 11, 2010 | Goole A.F.C. | v | Belper Town | Evo-Stik League Division One South | |
| Saturday, September 18, 2010 | Goole A.F.C. | v | Grantham Town | Evo-Stik League Division One South | |
| Tuesday, September 21, 2010 | Goole A.F.C. | v | Harrogate Railway | Northern Premier League - League Cup | |
| Tuesday, September 28, 2010 | Goole A.F.C. | v | Glapwell | Evo-Stik League Division One South | |
| Tuesday, October 5, 2010 | Goole A.F.C. | v | Newcastle Town | FA Trophy | |
| Saturday, October 9, 2010 | Goole A.F.C. | v | Leek Town | Evo-Stik League Division One South | |
| Saturday, October 30, 2010 | Goole A.F.C. | v | Loughborough | Evo-Stik League Division One South | |
| Tuesday, November 2, 2010 | Goole A.F.C. | v | Silsden | West Riding County Cup | |
| Saturday, November 13, 2010 | Goole A.F.C. | v | Carlton Town | Evo-Stik League Division One South | |
| Thursday, November 18, 2010 | Goole A.F.C. | v | Sheffield FC | Evo-Stik League Challenge Cup | |
| Tuesday, November 30, 2010 | Goole A.F.C. | v | Harrogate Town | West Riding County Cup | |
| Monday, December 27, 2010 | Goole A.F.C. | v | Brigg Town | Evo-Stik League Division One South | |
| Monday, January 3, 2011 | Goole A.F.C. | v | Shepshed Dynamo | Evo-Stik League Division One South | |
| Saturday, January 15, 2011 | Goole A.F.C. | v | Romulus | Evo-Stik League Division One South | |
| Tuesday, January 18, 2011 | Goole A.F.C. | v | Lincoln United | Evo-Stik League Division One South | |
| Saturday, January 29, 2011 | Goole A.F.C. | v | Quorn | Evo-Stik League Division One South | |
| Tuesday, February 1, 2011 | Goole A.F.C. | v | Askern Villa | West Riding County Cup | |
| Saturday, February 5, 2011 | Goole A.F.C. | v | Sheffield FC | Evo-Stik League Division One South | |
| Tuesday, February 15, 2011 | Goole A.F.C. | v | Stamford | Evo-Stik League Division One South |