Changing the toilet paper will not cause Brain Damage / 6x6 Wood Sign // Second Nature by Hand product is Made in the USA by skilled craftsmen in IA and WI. We source distressed natural reclaimed materials throughout North America that ensures no two Second Nature by Hand signs in the world are the same. The wood for this sign may have come from a ship yard, old factory or a huge variety of other sources. Buying reclaimed wood products is good for the environment. Due to the reclaimed nature of this product, colors and wood tones/features may vary slightly.