Edna Fischer's radio career began in 1918, at Berkeley's Claremont Hotel, where she participated in an experimental broadcast. "It was some sort of experimental station – I think it became KRE later on," she recalled. "In 1926," she said, "I suffered a multiple fracture of my right wrist in a car crash, canceled some East Coast appearances, and while I was recuperating, Fred Sherman (of San Francisco's Sherman, Clay & Co.) encouraged me to get into radio at KFRC." KFRC-AM (610 kHz) then broadcast from studios in the plush Don Lee Cadillac building at 1000 Van Ness Ave. There, she became a regular on "Blue Monday Jamboree," one of the earliest and most popular local radio programs in the history of San Francisco radio, where she starred with Tommy Harris and Morey Amsterdam. She recorded The Varsity Drag and Rag Doll in Oakland and both were released as Victor 21380 in 1928. On October 1, 1938, then-mayor of San Francisco Dianne Feinstein officially proclaimed that day as "Edna Fischer Day."