Rituximab
by Gerond V. Lake-Bakaar
Rituximab (MabThera(r), Rituxan(r)) is a chimaeric murine/human antibody targeted against the surface antigen CD20 that is expressed on normal and malignant human mature B cells, but not stem cells or plasma cells. It is potentially the proverbial magic bullet for diseases associated with B cell disorders as well as a probe for elucidating the role of B cells in health and disease. This book explores the full spectrum of activity of Rituximab in man.
Paperback
English
Brand New
Publisher Description
Rituximab (MabThera(R), Rituxan(R)) is a chimaeric murine/human antibody targeted against the surface antigen CD20 that is expressed on normal and malignant human mature B cells, but not stem cells or plasma cells. It is potentially the proverbial magic bullet for diseases associated with B cell disorders as well as a probe for elucidating the role of B cells in health and disease. This book explores the full spectrum of activity of Rituximab in man.
Author Biography
Gerond V. Lake-Bakaar, M.D., Ph.D. (Liver Center, Beth Israel Deaconess Medical Center, Boston, MA, USA)
Table of Contents
Preface; Introduction; Introduction to Rituximab: The magic B cell Bullet; RITUXIMAB: Pharmacology, Clinical Indications & Health Benefits; Rituximab: update on pharmacology & clinical applications; Rituximab in the treatment of Hematological Malignancies; The Use of Rituximab in Rheumatoid Arthritis; Rituximab induced Late-onset Neutropenia.
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