Publisher Description

Aluminium is the most abundant metal ion in the biosphere and we are continuously exposed to it in our everyday life through things like food, beverages, and pharmaceutical products. This book is a review of the biochemistry, metabolism and toxicity of aluminium undertaken by an international group of authors, who are authorities in their respective fields. The text is primarily directed at aluminium nutrition and toxicity in infants and children. It covers many aspects of aluminium toxicity in infants including, for instance, the embryo-foetal as well as the neurodevelopmental effects of this element, contamination of pharmaceutical products, and individual sensitivity through vaccines using aluminium as an adjuvant.

Table of Contents

Part 1 Chemistry, biochemistry and physiology: the importance of aluminium chemistry in biological systems, R.B. Martin; aluminium-26 as a biological tracer using accelerator mass spectrometry, R. Flack and D. Elmore; aluminium toxicity depends on the metal speciation, P.F. Zatta and P. Zambenedetti; aluminium metabolism, A.C. Alfrey; aluminium and iron relationship - pathophysiological and clinical overview, J.B. Cannata Andia. Part 2 Paediatrics: aluminium in infancy, K. Simmer; aluminium toxicity in infants, M. McGraw; aluminium-related bone disease in children with renal failure, B.D. Kuizon and I.B. Salusky; aluminium and antiacids in infants, J.W.L. Puntis; development and aluminium experimental toxicity, J.L. Domingo. Part 3 Paediatric pharmacology: aluminium content of parental nutrition products, G.L. Klein; aluminium content in the intravenous treatment in infants, A. Moreno et al; aluminium in human albumin solutions, B. Gammelgaard and O. Jons; reduction of aluminium levels in albumin products, Y. Uemura et al; toxicity of aluminium compounds as an adjuvant for vaccines, N. Goto; a public health analysis of dietary aluminium, S. Humphreys and P.M. Bolger.

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