Paris, Veuve Méquignon et Didot le Jeune, 1777. First Edition.
Volume 1 only of two-volume work.
Contemporary full leather binding, gilt decorated spine with title label, marbled edges and end papers, duodecimo (6.7 inches tall), xxv pages, (1) page of errata, 30 page introductory letter, 360 pages.
In French.

First edition of the most famous work of Dr. Pierre-Toussaint Navier (1712-1779), doctor of King Louis XVI.

Edition originale du livre le plus réputé du Docteur Pierre-Toussaint Navier, médecin du roi Louis XVI. 

This, the first volume, treats antidotes to poisoning by Arsenic, Mercuric Chloride and Verdigris (Copper Carbonate) which was commonly used as a pigment.
The antidotes to lead poisoning and the 3 dissertations mentioned on the title page are treated in Volume II (which we do not have).

Pierre-Toussaint NAVIER, (1712-1779), doctor in Châlons-sur-Marne, made famous by fighting against serious epidemics which raged in Champagne at this time (1740-1760). But it is his treatise of poison antidotes which assured him the notoriety in all the kingdom. An eminent chemist, he distinguished himself by his experiments on alkaline, calcareous and martial hepar (hydrogenated sulphides of potash, lime and iron) and their action against arsenic. He was also the first to advise the use of copper utensils in contact with food ... -

"This work, drawn from the most profound chemistry, and the fruit of more than thirty years of study, still enjoys a well-deserved esteem;…..”

Pierre-Toussaint Navier, born in St-Dizier on November 1, 1712, received a doctorate in medicine in Reims in 1741. He chose Châlons-sur-Marne for the place of his residence, and soon earned the title of correspondent of the Royal Academy of Science, by a memoir containing the discovery of the nitrous ether. Since that time each year of his life was marked by new memoirs or dissertations, which are found inserted in the Collections of the Academy of Sciences, the Academy of Chalons, and in the Gazette de Medecine. Always animated by the love of the public good and the desire to contribute to the progress of sciences and arts, he undertook to fix them among his new fellow citizens, by forming, with Dupré d'Ornay and others, the project of a a literary society which began its sittings in 1753, and which was erected in the month of August, 1775, as an academy of sciences, arts, and belles-lettres. Louis XVI gave him a pension in 1779.