Autor(en)

Tauber, Alfred I. and Scott H. Podolsky:

Verlag / Jahr

Cambridge, London: Harvard University Press, 2000.

Format / Einband

Paperback. 508 p.

Sprache

Englisch

Gewicht

ca. 621 g

ISBN

0674001826

EAN

9780674001824

Bestell-Nr

1191651

Bemerkungen

Aus der Bibliothek von Prof. Wolfgang Haase, langjährigem Herausgeber der ANRW und des International Journal of the Classical Tradition (IJCT) / From the library of Prof. Wolfgang Haase, long-time editor of ANRW and the International Journal of the Classical Tradition (IJCT). - Einband leicht berieben, Buchrücken leicht ausgeblichen, Bleistiftanmerkung auf Titelblatt, sonst guter Zustand / binding slightly rubbed, spine slightly faded, pencil annotation on title page, otherwise good condition. - In recent decades immunology has been one of the most exciting—and successful—fields of biomedical research. Over the past thirty years immunologists have acquired a detailed understanding of the immune system's unique recognition mechanism and of the cellular and chemical means used to destroy or neutralize invading organisms. This understanding has been formulated in terms of the clonal selection theory, the dominant explanation of immune behavior. That story is the subject of The Generation of Diversity. This book is an intellectual history of the major theoretical problem in immunology and its resolution in the post-World War II period. It will provide for immunologists essential background for understanding the conceptual conflicts occurring in the field today. / Contents Acknowledgments ix Introduction 1 Prelude: A Conceptual Orientation 1 The Burnet Legacy 2 CST and Molecular Immunology—A Dogmatic Alliance Interlude: The Conventional History 3 Germline, Somatic Mutation, and Recombinatorial Models: 1960-1974 4 Immunobiological Theories of Antibody Diversity 5 From Protein to DNA 6 The Recombinant Revolution Interlude: A Historiographic Reappraisal 7 Heavy Chain Diversity and the Molecular Finale 8 An Accounting 9 The Fate of the Immune Self Notes References Index. ISBN 9780674001824

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